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Author Anisimov, V. N.
Title Light pollution, reproductive function and cancer risk Type Journal Article
Year 2006 Publication Neuroendocrinology Letters Abbreviated Journal (up)
Volume 27 Issue 1-2 Pages 35-52
Keywords Human Health
Abstract At present, light pollution (exposure to light-at-night) both in the form of occupational exposure during night work and as a personal choice and life style, is experienced by numerous night-active members of our society. Disruption of the circadian rhythms induced by light pollution has been associated with cancer in humans. There are epidemiological evidences of increased breast and colon cancer risk in shift workers. An inhibition of the pineal gland function with exposure to the constant light (LL) regimen promoted carcinogenesis whereas the light deprivation inhibits the carcinogenesis. Treatment with pineal indole hormone melatonin inhibits carcinogenesis in pinealectomized rats or animals kept at the standard light/dark regimen (LD) or at the LL regimen. These observations might lead to use melatonin for cancer prevention in groups of humans at risk of light pollution.
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Call Number LoNNe @ kagoburian @ Serial 703
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Author Aschoff, J. ,
Title Der Tagesgang der Körpertemperatur beim Menschen, Type Journal Article
Year 1955 Publication Klinische Wochenschrift Abbreviated Journal (up)
Volume 33 Issue 23/24 Pages 545-551
Keywords Human Health
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Call Number LoNNe @ kagoburian @ Serial 707
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Author Aschoff, J.
Title Exogene und endogene Komponente der 24-Stunden-Periodik bei Tier und Mensch Type Journal Article
Year 1955 Publication Die Naturwissenschaften Abbreviated Journal (up)
Volume 42 Issue 21 Pages 569-575
Keywords Human Health; Animals
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Call Number LoNNe @ kagoburian @ Serial 708
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Author Aschoff, J.
Title Aktivitätsmuster der Tagesperiodik Type Journal Article
Year 1957 Publication Die Naturwissenschaften Abbreviated Journal (up)
Volume 44 Issue 13 Pages 361-367
Keywords Human Health
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Call Number LoNNe @ kagoburian @ Serial 709
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Author Benot, S.; R. Goberna; R. J. Reiter; S. Garcia-Mauriño; C. Osuna; J. M. Guerrero
Title Physiological levels of melatonin contribute to the antioxidant capacity of human serum Type Journal Article
Year 1999 Publication Journal of Pineal Research Abbreviated Journal (up)
Volume 27 Issue Pages 59-64
Keywords Human Health
Abstract This work evaluates whether physiological concentrations of the pineal secretory product melatonin contribute to the total antioxidant status (TAS) of human serum. Day and nighttime serum samples were collected from healthy volunteers ranging from 2 to 89 years of age and used to measure melatonin and TAS. Results showed that both melatonin and TAS in human serum exhibited 24 hr variations with nocturnal peak values at 01:00 hr. Moreover, exposure of volunteers to light at night resulted in clear decreases of both TAS and melatonin. Furthermore, when melatonin was removed from sera collected at night, the TAS value of the sample was reduced to basal daytime values. In aging studies, it was found that nocturnal serum values of TAS and melatonin exhibited maximal values during the first four decades; thereafter, these values decreased as age advanced. In 60-year-old individuals, day/night differences in serum melatonin and TAS levels were clearly diminished, by more than 80%, with these differences being completely abolished in older individuals. Our results suggest that melatonin contributes to the total antioxidative capability of human serum. This antioxidant contribution of melatonin is reduced as age advances correlating with the age-related reduction of melatonin.
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Call Number LoNNe @ kagoburian @ Serial 719
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