| |
Records |
Links |
|
Author |
Chellappa, S.L.; Steiner, R.; Oelhafen, P.; Lang, D.; Gotz, T.; Krebs, J.; Cajochen, C. |
|
| |
Title  |
Acute exposure to evening blue-enriched light impacts on human sleep |
Type |
Journal Article |
| |
Year |
2013 |
Publication |
Journal of Sleep Research |
Abbreviated Journal |
J Sleep Res |
|
| |
Volume |
22 |
Issue |
5 |
Pages |
573-580 |
|
| |
Keywords |
Human Health |
|
| |
Abstract |
Light in the short wavelength range (blue light: 446-483 nm) elicits direct effects on human melatonin secretion, alertness and cognitive performance via non-image-forming photoreceptors. However, the impact of blue-enriched polychromatic light on human sleep architecture and sleep electroencephalographic activity remains fairly unknown. In this study we investigated sleep structure and sleep electroencephalographic characteristics of 30 healthy young participants (16 men, 14 women; age range 20-31 years) following 2 h of evening light exposure to polychromatic light at 6500 K, 2500 K and 3000 K. Sleep structure across the first three non-rapid eye movement non-rapid eye movement – rapid eye movement sleep cycles did not differ significantly with respect to the light conditions. All-night non-rapid eye movement sleep electroencephalographic power density indicated that exposure to light at 6500 K resulted in a tendency for less frontal non-rapid eye movement electroencephalographic power density, compared to light at 2500 K and 3000 K. The dynamics of non-rapid eye movement electroencephalographic slow wave activity (2.0-4.0 Hz), a functional index of homeostatic sleep pressure, were such that slow wave activity was reduced significantly during the first sleep cycle after light at 6500 K compared to light at 2500 K and 3000 K, particularly in the frontal derivation. Our data suggest that exposure to blue-enriched polychromatic light at relatively low room light levels impacts upon homeostatic sleep regulation, as indexed by reduction in frontal slow wave activity during the first non-rapid eye movement episode. |
|
| |
Address |
Centre for Chronobiology, Psychiatric Hospital of the University of Basel, Basel, Switzerland; Cyclotron Research Center, University of Liege, Liege, Belgium |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0962-1105 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:23509952 |
Approved |
no |
|
| |
Call Number |
GFZ @ kyba @ |
Serial |
2201 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Walker, W.H. 2nd; Borniger, J.C.; Gaudier-Diaz, M.M.; Hecmarie Melendez-Fernandez, O.; Pascoe, J.L.; Courtney DeVries, A.; Nelson, R.J. |
|
| |
Title |
Acute exposure to low-level light at night is sufficient to induce neurological changes and depressive-like behavior |
Type |
Journal Article |
| |
Year |
2019 |
Publication |
Molecular Psychiatry |
Abbreviated Journal |
Mol Psychiatry |
|
| |
Volume |
|
Issue |
|
Pages |
s41380-019-0430-4 |
|
| |
Keywords |
Human health; physiology; brain |
|
| |
Abstract |
The advent and wide-spread adoption of electric lighting over the past century has profoundly affected the circadian organization of physiology and behavior for many individuals in industrialized nations; electric lighting in homes, work environments, and public areas have extended daytime activities into the evening, thus, increasing night-time exposure to light. Although initially assumed to be innocuous, chronic exposure to light at night (LAN) is now associated with increased incidence of cancer, metabolic disorders, and affective problems in humans. However, little is known about potential acute effects of LAN. To determine whether acute exposure to low-level LAN alters brain function, adult male, and female mice were housed in either light days and dark nights (LD; 14 h of 150 lux:10 h of 0 lux) or light days and low level light at night (LAN; 14 h of 150 lux:10 h of 5 lux). Mice exposed to LAN on three consecutive nights increased depressive-like responses compared to mice housed in dark nights. In addition, female mice exposed to LAN increased central tendency in the open field. LAN was associated with reduced hippocampal vascular endothelial growth factor-A (VEGF-A) in both male and female mice, as well as increased VEGFR1 and interleukin-1beta mRNA expression in females, and reduced brain derived neurotrophic factor mRNA in males. Further, LAN significantly altered circadian rhythms (activity and temperature) and circadian gene expression in female and male mice, respectively. Altogether, this study demonstrates that acute exposure to LAN alters brain physiology and can be detrimental to well-being in otherwise healthy individuals. |
|
| |
Address |
Department of Rockefeller Neuroscience Institute, West Virginia University, Morgantown, WV, 26506, USA |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
Nature |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
1359-4184 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:31138889 |
Approved |
no |
|
| |
Call Number |
IDA @ john @ |
Serial |
2509 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Walker, W.H. 2nd; Borniger, J.C.; Gaudier-Diaz, M.M.; Hecmarie Melendez-Fernandez, O.; Pascoe, J.L.; Courtney DeVries, A.; Nelson, R.J. |
|
| |
Title |
Acute exposure to low-level light at night is sufficient to induce neurological changes and depressive-like behavior |
Type |
Journal Article |
| |
Year |
2019 |
Publication |
Molecular Psychiatry |
Abbreviated Journal |
Mol Psychiatry |
|
| |
Volume |
|
Issue |
|
Pages |
s41380 |
|
| |
Keywords |
Animals; mouse models; mood disorders; Human Health |
|
| |
Abstract |
The advent and wide-spread adoption of electric lighting over the past century has profoundly affected the circadian organization of physiology and behavior for many individuals in industrialized nations; electric lighting in homes, work environments, and public areas have extended daytime activities into the evening, thus, increasing night-time exposure to light. Although initially assumed to be innocuous, chronic exposure to light at night (LAN) is now associated with increased incidence of cancer, metabolic disorders, and affective problems in humans. However, little is known about potential acute effects of LAN. To determine whether acute exposure to low-level LAN alters brain function, adult male, and female mice were housed in either light days and dark nights (LD; 14 h of 150 lux:10 h of 0 lux) or light days and low level light at night (LAN; 14 h of 150 lux:10 h of 5 lux). Mice exposed to LAN on three consecutive nights increased depressive-like responses compared to mice housed in dark nights. In addition, female mice exposed to LAN increased central tendency in the open field. LAN was associated with reduced hippocampal vascular endothelial growth factor-A (VEGF-A) in both male and female mice, as well as increased VEGFR1 and interleukin-1beta mRNA expression in females, and reduced brain derived neurotrophic factor mRNA in males. Further, LAN significantly altered circadian rhythms (activity and temperature) and circadian gene expression in female and male mice, respectively. Altogether, this study demonstrates that acute exposure to LAN alters brain physiology and can be detrimental to well-being in otherwise healthy individuals. |
|
| |
Address |
Department of Rockefeller Neuroscience Institute, West Virginia University, Morgantown, WV, 26506, USA |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
1359-4184 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:31138889; PMCID:PMC6881534 |
Approved |
no |
|
| |
Call Number |
GFZ @ kyba @ |
Serial |
2768 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Takemura, Y.; Ito, M.; Shimizu, Y.; Okano, K.; Okano, T. |
|
| |
Title |
Adaptive light: a lighting control method aligned with dark adaptation of human vision |
Type |
Journal Article |
| |
Year |
2020 |
Publication |
Scientific Reports |
Abbreviated Journal |
Sci Rep |
|
| |
Volume |
10 |
Issue |
1 |
Pages |
11204 |
|
| |
Keywords |
Human Health; Vision; Lighting |
|
| |
Abstract |
Light exposure before sleep causes a reduction in the quality and duration of sleep. In order to reduce these detrimental effects of light exposure, it is important to dim the light. However, dimming the light often causes inconvenience and can lower the quality of life (QOL). We therefore aimed to develop a lighting control method for use before going to bed, in which the illuminance of lights can be ramped down with less of a subjective feeling of changes in illuminance. We performed seven experiments in a double-blind, randomized crossover design. In each experiment, we compared two lighting conditions. We examined constant illuminance, linear dimming, and three monophasic and three biphasic exponential dimming, to explore the fast and slow increases in visibility that reflect the dark adaptation of cone and rod photoreceptors in the retina, respectively. Finally, we developed a biphasic exponential dimming method termed Adaptive Light 1.0. Adaptive Light 1.0 significantly prevented the misidentification seen in constant light and effectively suppressed perceptions of the illuminance change. This novel lighting method will help to develop new intelligent lighting instruments that reduce the negative effect of light on sleep and also lower energy consumption. |
|
| |
Address |
The Smart Life Science Institute, ACROSS, Waseda University, Tokyo, Japan. okano@waseda.jp |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
2045-2322 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:32641723; PMCID:PMC7343865 |
Approved |
no |
|
| |
Call Number |
GFZ @ kyba @ |
Serial |
3050 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Peixoto, C.A.T.; da Silva, A.G.T.; Carskadon, M.A.; Louzada, F.M. |
|
| |
Title |
Adolescents living in homes without electric lighting have earlier sleep times |
Type |
Journal Article |
| |
Year |
2009 |
Publication |
Behavioral Sleep Medicine |
Abbreviated Journal |
Behav Sleep Med |
|
| |
Volume |
7 |
Issue |
2 |
Pages |
73-80 |
|
| |
Keywords |
Human Health; Sleep |
|
| |
Abstract |
The aim of this project was to compare circadian rhythmicity of a group of 37 adolescents (14 girls), aged 11 to 16 (mean age = 13.1 +/- 1.7 years), with and without electricity at home. Twenty students attended morning school (07:30-11:30), and 17 attended evening school classes (19:00-22:30). Eleven adolescents had no electric lighting at home (5 attended morning classes and 6 attended evening classes). They completed a sleep log and wore a wrist actigraph for 5 consecutive days. Saliva samples were collected to assess DLMO. Data were compared by ANOVA and showed later timing and a more extended sleep period for those who attended late classes. Those adolescents without electricity at home had significantly earlier sleep onset on school days. As to DLMO, a trend to a delay was observed in the groups who had electric lighting. |
|
| |
Address |
Department of Physiology, Universidade Federal do Parana, Brazil. pedatardelli@yahoo.com.br |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
1540-2002 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:19330580 |
Approved |
no |
|
| |
Call Number |
LoNNe @ kyba @ |
Serial |
1481 |
|
| Permanent link to this record |
