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Author Zhang, D.; Jones, R.R.; Powell-Wiley, T.M.; Jia, P.; James, P.; Xiao, Q. url  doi
openurl 
  Title (up) A large prospective investigation of outdoor light at night and obesity in the NIH-AARP Diet and Health Study Type Journal Article
  Year 2020 Publication Environmental Health : a Global Access Science Source Abbreviated Journal Environ Health  
  Volume 19 Issue 1 Pages 74  
  Keywords Human Health; Remote Sensing; Circadian rhythms; Light at night; Light pollution; Obesity  
  Abstract BACKGROUND: Research has suggested that artificial light at night (LAN) may disrupt circadian rhythms, sleep, and contribute to the development of obesity. However, almost all previous studies are cross-sectional, thus, there is a need for prospective investigations of the association between LAN and obesity risk. The goal of our current study was to examine the association between baseline LAN and the development of obesity over follow-up in a large cohort of American adults. METHODS: The study included a sample of 239,781 men and women (aged 50-71) from the NIH-AARP Diet and Health Study who were not obese at baseline (1995-1996). We used multiple logistic regression to examine whether LAN at baseline was associated with the odds of developing obesity at follow-up (2004-2006). Outdoor LAN exposure was estimated from satellite imagery and obesity was measured based on self-reported weight and height. RESULTS: We found that higher outdoor LAN at baseline was associated with higher odds of developing obesity over 10 years. Compared with the lowest quintile of LAN, the highest quintile was associated with 12% and 19% higher odds of developing obesity at follow-up in men (OR (95% CI) = 1.12 (1.00, 1.250)) and women (1.19 (1.04, 1.36)), respectively. CONCLUSIONS: Our findings suggest that high LAN exposure could predict a higher risk of developing obesity in middle-to-older aged American adults.  
  Address Department of Epidemiology, Human Genetics and Environmental Sciences, The University of Texas Health Science Center at Houston School of Public Health, Houston, TX, USA  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
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  Series Volume Series Issue Edition  
  ISSN 1476-069X ISBN Medium  
  Area Expedition Conference  
  Notes PMID:32611430; PMCID:PMC7329409 Approved no  
  Call Number GFZ @ kyba @ Serial 3029  
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Author Fasciani, I.; Petragnano, F.; Aloisi, G.; Marampon, F.; Rossi, M.; Francesca Coppolino, M.; Rossi, R.; Longoni, B.; Scarselli, M.; Maggio, R. url  doi
openurl 
  Title (up) A new threat to dopamine neurons: the downside of artificial light Type Journal Article
  Year 2020 Publication Neuroscience Abbreviated Journal Neuroscience  
  Volume in press Issue Pages in press  
  Keywords Review; Human Health; Parkinson's disease; artificial light; dopamine neurons; melatonin; opsins; photoactivation  
  Abstract Growing awareness of adverse impacts of artificial light on human health has led to recognize light pollution as a significant global environmental issue. Despite, a large number of studies in rodent and monkey models of Parkinson's disease have reported that near infrared light has neuroprotective effects on dopaminergic neurons, recent findings have shown that prolonged exposure of rodents and birds to fluorescent artificial light results in an increase of neuromelanin granules in substantia nigra and loss of dopaminergic neurons. The observed detrimental effect seems to be dependent on a direct effect of light on the substantia nigra rather than a secondary effect of the alterations of circadian rhythms. Moreover, inferences from animal models to human studies have shown a positive correlation between the prevalence of Parkinson's disease and light pollution. The present article discusses experimental evidence supporting a potentially deleterious impact of light on dopaminergic neurons and highlights the mechanisms whereby light might damage neuronal tissue. Moreover, it analyses epidemiological evidence that suggests light pollution to be an environmental risk factor for Parkinson's disease.  
  Address Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy. Electronic address: roberto.maggio@univaq.it  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0306-4522 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:32142863 Approved no  
  Call Number GFZ @ kyba @ Serial 2839  
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Author Provencio, I.; Rodriguez, I.R.; Jiang, G.; Hayes, W.P.; Moreira, E.F.; Rollag, M.D. url  openurl
  Title (up) A Novel Human Opsin in the Inner Retina. Type Journal Article
  Year 2000 Publication Abbreviated Journal  
  Volume 20 Issue 2 Pages 600-605  
  Keywords Human Health  
  Abstract Here we report the identification of a novel human opsin, melanopsin, that is expressed in cells of the mammalian inner retina. The human melanopsin gene consists of 10 exons and is mapped to chromosome 10q22. This chromosomal localization and gene structure differs significantly from that of other human opsins that typically have four to seven exons. A survey of 26 anatomical sites indicates that, in humans, melanopsin is expressed only in the eye. In situ hybridization histochemistry shows that melanopsin expression is restricted to cells within the ganglion and amacrine cell layers of the primate and murine retinas. Notably, expression is not observed in retinal photoreceptor cells, the opsin-containing cells of the outer retina that initiate vision. The unique inner retinal localization of melanopsin suggests that it is not involved in image formation but rather may mediate nonvisual photoreceptive tasks, such as the regulation of circadian rhythms and the acute suppression of pineal melatonin. The anatomical distribution of melanopsin-positive retinal cells is similar to the pattern of cells known to project from the retina to the suprachiasmatic nuclei of the hypothalamus, a primary circadian pacemaker.  
  Address  
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  Area Expedition Conference  
  Notes Approved no  
  Call Number LoNNe @ christopher.kyba @ Serial 530  
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Author Phelps, J. url  doi
openurl 
  Title (up) A powerful non-pharmacologic treatment for mania – virtually Type Journal Article
  Year 2016 Publication Bipolar Disorders Abbreviated Journal Bipolar Disord  
  Volume 18 Issue 4 Pages 379-382  
  Keywords Commentary; Human Health  
  Abstract  
  Address Samaritan Mental Health, Corvallis, OR, USA  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1398-5647 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:27218661 Approved no  
  Call Number LoNNe @ kyba @ Serial 1511  
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Author Ticleanu, C.; Littlefair, P. url  openurl
  Title (up) A summary of LED lighting impacts on health Type Journal Article
  Year 2015 Publication International Journal of Sustainable Lighting Abbreviated Journal Intl. J. of Sustainable Lighting  
  Volume 1 Issue 1 Pages 5-11  
  Keywords Human health; light and health; LED glare; LED flicker; melatonin supression; LED skin exposure  
  Abstract Lighting can affect the health of people in buildings. This goes beyond the safety aspects of providing enough illumination to see by; lighting affects mood and human circadian rhythms, while poor lighting can cause glare, headaches, eyestrain, aches and pains associated with poor body posture or, in extreme cases, skin conditions and various types of sight loss. These aspects ought to be considered by designers and building owners and occupiers in order to improve the lit environment and use adequate lighting and lighting controls that meet the recommendations of codes and standards. Various types of lighting can have different impacts depending on their spectral, optical and electrical characteristics. This paper discusses potential impacts of LED lighting on human health, and is based on a recent BRE review of research investigating the most typical effects of lighting on human health.  
  Address Building Research Establishment (BRE), Bucknalls Lane, Watford WD25 9XX UK; Cosmin.Ticleanu(at)bre.co.uk  
  Corporate Author Thesis  
  Publisher International Journal of Sustainable Lighting Place of Publication Editor  
  Language English Summary Language English Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1454-5837 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number IDA @ john @ Serial 1389  
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