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Author Padilla-Martinez, J.M.; Abad-Corpa, E.; Gea-Sanchez, M.; Casado-Ramirez, E.; Rol-de Lama, M.A.; Madrid-Perez, J.A.; Moreno-Casbas, M.T. url  doi
openurl 
  Title “Detection of factors influencing circadian rhythms on Intensive Care inpatients and hospitalization: Protocol for an observational study” Type Journal Article
  Year 2020 Publication Journal of Advanced Nursing Abbreviated Journal J Adv Nurs  
  Volume in press Issue Pages in press  
  Keywords Human Health; care; circadian rhythm; hospitalization; light; noise; nursing; nursing activities; protocol; sleep quality  
  Abstract AIMS: Identify the prevalence of circadian health disorders in ICU and hospitalized patients. Stablish the relationship of the circadian system with light, temperature, noise and nursing activities. BACKGROUND: Commonly, self-assessment through subjective questionnaires is used for research about sleep quality. However, more reliable and valid measures should be applied objectively to find out the real prevalence of the problem. There is a negative relationship between circadian rhythms and hospitalization. In this study, we will analyse sleep patterns and hospital environments to implement measures to improve the quality of care related to sleep. DESIGN: Descriptive observational study. It is estimated that 975 patients from 13 hospitals need to be recruited from ICU and hospitalization units. The sample should meet the following criteria: Patients over 18 admitted to ICU and medical units, length of stay between 96-148 hr, with no visual, hearing or moderate-severe cognitive impairment. Variables: Sleep variables are collected with an electronic device (named Kronowise(R) and Kronobed(R)), circadian and infrared light exposure, environmental noise, temperature, unit structural characteristics, nursing care (from 0 to 6 a.m.) and, characteristics of hospitalization period. The study, registered on Clinical Trials, initiated in December 2019 and it will continue up to December 2022. DISCUSSION: Using objective and subjective measures of sleep and circadian rhythms, this study will shed light on the factors that negatively affect the hospitalized patients' sleep quality and circadian health. The ultimate goal is to design hospital guidelines to minimize the adverse effects on the dependent variables studied. Arguably, these guidelines will contribute to reducing the risk of these alterations and it will also serve to improve the nursing activities. CONCLUSION: We expect to obtain adequate results for the creation of a protocol to improve the circadian health, quality of care and health outcomes related to sleep in patients.  
  Address Biomedical Research Center for Fragility and Healthy Aging (CIBERFES), Madrid, Spain  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0309-2402 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:32996642 Approved no  
  Call Number GFZ @ kyba @ Serial 3165  
Permanent link to this record
 

 
Author Rea, M.S.; Nagare, R.; Figueiro, M.G. url  doi
openurl 
  Title Predictions of melatonin suppression during the early biological night and their implications for residential light exposures prior to sleeping Type Journal Article
  Year 2020 Publication Scientific Reports Abbreviated Journal Sci Rep  
  Volume 10 Issue 1 Pages 14114  
  Keywords Human Health  
  Abstract The magnitude of nocturnal melatonin suppression depends upon the spectrum, amount, and duration of light exposure. The functional relationship between melatonin suppression and the light spectrum and amount have been previously described. Only one duration-dependent parameter was needed to extend this functional relationship to predict nocturnal melatonin suppression during the early biological night from a variety of published studies. Those predictions suggest that ambient lighting commonly found in North American homes will not suppress melatonin for durations up to 3 h, whereas extended use of self-luminous displays in the home prior to sleep can.  
  Address Lighting Research Center, Rensselaer Polytechnic Institute, 21 Union Street, Troy, NY, 12180-3352, USA  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2045-2322 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:32839489; PMCID:PMC7445277 Approved no  
  Call Number GFZ @ kyba @ Serial 3098  
Permanent link to this record
 

 
Author Torriglia, A.; Mascarelli, F.; Behar-Cohen, F. url  doi
openurl 
  Title [New lighting technology and our eyes] Type Journal Article
  Year 2020 Publication Medecine Sciences : M/S Abbreviated Journal Med Sci (Paris)  
  Volume 36 Issue 8-9 Pages 769-773  
  Keywords Review; Human Health  
  Abstract The retina is the neurosensitive layer of the eye. In this tissue, photoreceptors convert light into nerve signals to be relayed to the brain. Despite retinal specialization in the treatment of light, excessive exposure can cause retinal damage, called retinal phototoxicity. In recent years, lighting devices rich in wavelengths of high energy (blue light) appeared, raising new concerns about retinal protection against light damage. We focus here on light-induced ocular diseases and the possible influence on visual health of new lighting technologies.

Dans la rétine, couche neurosensorielle de l’œil, les photorécepteurs transforment le signal lumineux en influx nerveux interprétable par le cerveau. Malgré sa spécialisation dans le traitement des signaux lumineux, la rétine peut subir des dommages, à la suite d’une exposition excessive à la lumière ; on parle alors de phototoxicité rétinienne. Ces dernières années, l’apparition de dispositifs d’éclairage riches en longueurs d’onde de forte énergie (ce que l’on nomme lumière bleue), remet le problème de la phototoxicité rétinienne à l’ordre du jour. Nous discutons des pathologies oculaires induites par la lumière et de la possible influence des nouvelles technologies d’éclairage sur notre santé visuelle.
 
  Address Centre de Recherche des Cordeliers, Inserm, Sorbonne Universite, USPC, universite de Paris Descartes, equipe << Physiopathologie des maladies oculaires : innovations therapeutiques >>, 15 rue de l'Ecole de Medecine, F-75006 Paris, France  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language French Summary Language Original Title Les nouveaux eclairages et nos yeux  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0767-0974 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:32821054 Approved no  
  Call Number GFZ @ kyba @ Serial 3097  
Permanent link to this record
 

 
Author Touitou, Y.; Point, S. url  doi
openurl 
  Title Effects and mechanisms of action of light-emitting diodes on the human retina and internal clock Type Journal Article
  Year 2020 Publication Environmental Research Abbreviated Journal Environ Res  
  Volume 190 Issue Pages in press  
  Keywords Review; Human Health; Biological clock; Blue light; Electronic media; Endocrine disruptor; Environmental synchronizers; Light at night; Melatonin; Night work; Retinal phototoxicity; Shift work; Sleep disorder  
  Abstract White light-emitting diodes (LEDs) will likely become the most used lighting devices worldwide in the future because of their very low prices over the course of their long lifespans which can be up to several tens of thousands of hours. The expansion of LED use in both urban and domestic lighting has prompted questions regarding their possible health effects, because the light that they provide is potentially high in the harmful blue band (400-500nm) of the visible light spectrum. Research on the potential effects of LEDs and their blue band on human health has followed three main directions: 1) examining their retinal phototoxicity; 2) examining disruption of the internal clock, i.e., an out-of-sync clock, in shift workers and night workers, including the accompanying health issues, most concerningly an increased relative risk of cancer; and 3) examining risky, inappropriate late-night use of smartphones and consoles among children and adolescents. Here, we document the recognized or potential health issues associated with LED lighting together with their underlying mechanisms of action. There is so far no evidence that LED lighting is deleterious to human retina under normal use. However, exposure to artificial light at night is a new source of pollution because it affects the circadian clock. Blue-rich light, including cold white LEDs, should be considered a new endocrine disruptor, because it affects estrogen secretion and has unhealthful consequences in women, as demonstrated to occur via a complex mechanism.  
  Address Cooper Securite SAS, 63200, Riom, France  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0013-9351 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:32758719 Approved no  
  Call Number GFZ @ kyba @ Serial 3091  
Permanent link to this record
 

 
Author Wieduwilt, A.; Alsat, E.A.; Blickwedel, J.; Strizek, B.; Di Battista, C.; Lachner, A.B.; Plischke, H.; Melaku, T.; Muller, A.; Bagci, S. url  doi
openurl 
  Title Dramatically altered environmental lighting conditions in women with high-risk pregnancy during hospitalization Type Journal Article
  Year 2020 Publication Chronobiology International Abbreviated Journal Chronobiol Int  
  Volume in press Issue Pages  
  Keywords Lighting; Human Health; Pregnant women; circadian rhythm; color temperatures; hospital light environmental; illuminance; indoor  
  Abstract The maternal circadian time structure is incredibly important in the entrainment and programing of the fetal and newborn circadian time structure. Natural sunlight is the primary environmental time cue for entrainment of circadian rhythms, but high-risk pregnant women spend most of their time indoors with artificial light sources and extremely low levels of natural light both during the day and night. Because the daily level, timing, duration of light exposure and its spectral properties are important in maintaining the normal circadian physiology in humans, we aimed to evaluate the environmental lighting conditions in high-risk pregnant women admitted to hospital for long-term stay. About 30 patients were included in the study. Exposed illuminance, color temperature and effective circadian radiation dose were measured and recorded every 10 s by light dosimeters attached to the patients' clothing. We documented the illuminance of 29 pregnant women on 235 inpatient days. Median (IQR) measured illuminance was 70 (28-173) lux in the morning, 124 (63-241) lux in the afternoon, 19 (6-53) lux in the evening and 0 (0-0) lux at the night. Median illuminance for the 235 inpatient days of assessment was below the recommended EU standard of 100 lux-60.5% of the mornings and 42.7% of the afternoons. The women confined to indoor locations rarely achieved an illuminances more than 300 lux in the morning and in the afternoon. Compared to women with outdoor mobility, those confined indoors have a significantly lower illuminance and color temperature, both in the morning and in the afternoon. Our study presents the first information about the dramatically altered environmental lighting conditions experienced by high-risk pregnant women during their hospital stay. Their exposure to light while in the hospital is significantly lower than exposure to natural daylight levels and below the recommended EU standard.  
  Address Department of Neonatology and Pediatric Intensive Care Medicine, Children's Hospital, University of Bonn , Bonn, Germany  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0742-0528 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:32752886 Approved no  
  Call Number GFZ @ kyba @ Serial 3061  
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