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Author (up) Abbott, S.M.; Malkani, R.G.; Zee, P.C. url  doi
openurl 
  Title Circadian disruption and human health: A bidirectional relationship Type Journal Article
  Year 2018 Publication The European Journal of Neuroscience Abbreviated Journal Eur J Neurosci  
  Volume in press Issue Pages  
  Keywords Human Health; Review  
  Abstract Circadian rhythm disorders have been classically associated with disorders of abnormal timing of the sleep-wake cycle, however circadian dysfunction can play a role in a wide range of pathology, ranging from the increased risk for cardiometabolic disease and malignancy in shift workers, prompting the need for a new field focused on the larger concept of circadian medicine. The relationship between circadian disruption and human health is bidirectional, with changes in circadian amplitude often preceding the classical symptoms of neurodegenerative disorders. As our understanding of the importance of circadian dysfunction in disease grows, we need to develop better clinical techniques for identifying circadian rhythms and also develop circadian based strategies for disease management. Overall this review highlights the need to bring the concept of time to all aspects of medicine, emphasizing circadian medicine as a prime example of both personalized and precision medicine.  
  Address Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0953-816X ISBN Medium  
  Area Expedition Conference  
  Notes PMID:30549337 Approved no  
  Call Number GFZ @ kyba @ Serial 2154  
Permanent link to this record
 

 
Author (up) Andreatta, G.; Tessmar-Raible, K. url  doi
openurl 
  Title The still dark side of the moon: molecular mechanisms of lunar-controlled rhythms and clocks Type Journal Article
  Year 2020 Publication Journal of Molecular Biology Abbreviated Journal J Mol Biol  
  Volume in press Issue Pages  
  Keywords Review; Animals; Hormones; Lunar rhythms; Physiology; Proteome; Transcriptome  
  Abstract Starting with the beginning of the last century, a multitude of scientific studies has documented that the lunar cycle times behaviors and physiology in many organisms. It is plausible that even the first life forms adapted to the different rhythms controlled by the moon. Consistently, many marine species exhibit lunar rhythms, and also the number of documented “lunar-rhythmic” terrestrial species is increasing. Organisms follow diverse lunar geophysical/astronomical rhythms, which differ significantly in terms of period length: from hours (circalunidian and circatidal rhythms) to days (circasemilunar and circalunar cycles). Evidence for internal circatital and circalunar oscillators exists for a range of species based on past behavioral studies, but those species with well-documented behaviorally free-running lunar rhythms are not typically used for molecular studies. Thus, the underlying molecular mechanisms are largely obscure: the dark side of the moon. Here we review findings which start to connect molecular pathways with moon-controlled physiology and behaviors. The present data indicate connections between metabolic/endocrine pathways and moon-controlled rhythms, as well as interactions between circadian and circatidal/circalunar rhythms. Moreover, recent high-throughput analyses provide useful leads towards pathways, as well as molecular markers. However, for each interpretation it is important to carefully consider the – partly substantially differing – conditions used in each experimental paradigm. In the future, it will be important to use lab experiments to delineate the specific mechanisms of the different solar- and lunar-controlled rhythms, but to also start integrating them together, as life has evolved equally long under rhythms of both sun and moon.  
  Address Max Perutz Labs, University of Vienna, Vienna BioCenter, Dr. Bohr-Gasse 9/4, A-1030 Vienna; Research Platform “Rhythms of Life”, University of Vienna, Vienna BioCenter, Dr. Bohr-Gasse 9/4, A-1030 Vienna. Electronic address: kristin.tessmar@mfpl.ac.at  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0022-2836 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:32198116 Approved no  
  Call Number GFZ @ kyba @ Serial 2865  
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Author (up) Anisimov, V. N. url  openurl
  Title Light desynchronosis and health Type Journal Article
  Year 2019 Publication Light & Engineering Abbreviated Journal  
  Volume 27 Issue 3 Pages 14-25  
  Keywords Human Health; Review  
  Abstract The review summarizes the modern knowledge of the impact of day-night, light-darkness rhythm disorders on the aging process and on the risk of development of the age-related conditions. Significant evidence has been obtained of that the constant artificial illumination and the daylight of the North has a stimulating effect on the occurrence and development of tumours in laboratory animals. It has been shown that long-term shift work, trans-meridian flights (jet-lag) and insomnia increase the risk of cardiovascular diseases, diabetes mellitus, and malignancies in humans. Particular attention is given to the studies where the relationship between light intensity, light wavelength and its ability to suppress the synthesis of melatonin produced at night in the pineal gland, are investigated. It has been established that melatonin synthesis is most effectively suppressed with blue light sources of a wavelength from 446 to 477 nm. The use of exogenous melatonin prevents premature aging of the reproductive system and the body as a whole prevents the development of immune-suppression, metabolic syndrome and tumours caused by light pollution. An urgent task is to develop recommendations for optimizing the illumination of workplaces and residential premises, of cities and towns as a prevention measure for premature aging and age-related pathology, which, ultimately, will contribute to the long-term maintaining of performance and improving the quality of life.  
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  Notes Approved no  
  Call Number IDA @ intern @ Serial 2642  
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Author (up) Aulsebrook, A.E.; Jones, T.M.; Mulder, R.A.; Lesku, J.A. url  doi
openurl 
  Title Impacts of artificial light at night on sleep: A review and prospectus Type Journal Article
  Year 2018 Publication Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology Abbreviated Journal J Exp Zool A Ecol Integr Physiol  
  Volume 329 Issue 8-9 Pages 409-418  
  Keywords Animals; Human Activities; Review  
  Abstract Natural cycles of light and darkness govern the timing of most aspects of animal behavior and physiology. Artificial light at night (ALAN)-a recent and pervasive form of pollution-can mask natural photoperiodic cues and interfere with biological rhythms. One such rhythm vulnerable to perturbation is the sleep-wake cycle. ALAN may greatly influence sleep in humans and wildlife, particularly in animals that sleep predominantly at night. There has been some recent evidence for impacts of ALAN on sleep, but critical questions remain. Some of these can be addressed by adopting approaches already entrenched in sleep research. In this paper, we review the current evidence for impacts of ALAN on sleep, highlight gaps in our understanding, and suggest opportunities for future research.  
  Address La Trobe University, School of Life Sciences, Melbourne, Victoria, Australia  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2471-5638 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:29869374 Approved no  
  Call Number GFZ @ kyba @ Serial 1933  
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Author (up) Barentine, J.C. url  doi
openurl 
  Title Methods for Assessment and Monitoring of Light Pollution around Ecologically Sensitive Sites Type Journal Article
  Year 2019 Publication Journal of Imaging Abbreviated Journal J. Imaging  
  Volume 5 Issue 5 Pages 54  
  Keywords Instrumentation; Skyglow; Remote Sensing; Review  
  Abstract Since the introduction of electric lighting over a century ago, and particularly in the decades following the Second World War, indications of artificial light on the nighttime Earth as seen from Earth orbit have increased at a rate exceeding that of world population growth during the same period. Modification of the natural photic environment at night is a clear and imminent consequence of the proliferation of anthropogenic light at night into outdoor spaces, and with this unprecedented change comes a host of known and suspected ecological consequences. In the past two decades, the conservation community has gradually come to view light pollution as a threat requiring the development of best management practices. Establishing those practices demands a means of quantifying the problem, identifying polluting sources, and monitoring the evolution of their impacts through time. The proliferation of solid-state lighting and the changes to source spectral power distribution it has brought relative to legacy lighting technologies add the complication of color to the overall situation. In this paper, I describe the challenge of quantifying light pollution threats to ecologically-sensitive sites in the context of efforts to conserve natural nighttime darkness, assess the current state of the art in detection and imaging technology as applied to this realm, review some recent innovations, and consider future prospects for imaging approaches to provide substantial support for darkness conservation initiatives around the world.  
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  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2313-433X ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number GFZ @ kyba @ Serial 2498  
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