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Author (up) Versteeg, R.I.; Stenvers, D.J.; Kalsbeek, A.; Bisschop, P.H.; Serlie, M.J.; la Fleur, S.E. url  doi
  Title Nutrition in the spotlight: metabolic effects of environmental light Type Journal Article
  Year 2016 Publication The Proceedings of the Nutrition Society Abbreviated Journal Proc Nutr Soc  
  Volume 75 Issue 4 Pages 451-463  
  Keywords Animals; Human Health  
  Abstract Use of artificial light resulted in relative independence from the natural light-dark (LD) cycle, allowing human subjects to shift the timing of food intake and work to convenient times. However, the increase in artificial light exposure parallels the increase in obesity prevalence. Light is the dominant Zeitgeber for the central circadian clock, which resides within the hypothalamic suprachiasmatic nucleus, and coordinates daily rhythm in feeding behaviour and metabolism. Eating during inappropriate light conditions may result in metabolic disease via changes in the biological clock. In this review, we describe the physiological role of light in the circadian timing system and explore the interaction between the circadian timing system and metabolism. Furthermore, we discuss the acute and chronic effects of artificial light exposure on food intake and energy metabolism in animals and human subjects. We propose that living in synchrony with the natural daily LD cycle promotes metabolic health and increased exposure to artificial light at inappropriate times of day has adverse effects on metabolism, feeding behaviour and body weight regulation. Reducing the negative side effects of the extensive use of artificial light in human subjects might be useful in the prevention of metabolic disease.  
  Address Department of Endocrinology & Metabolism,Academic Medical Center,University of Amsterdam,Meibergdreef 9,F2-154, 1105 AZ Amsterdam-Zuidoost,The Netherlands  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0029-6651 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:27499509 Approved no  
  Call Number LoNNe @ kyba @ Serial 1504  
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