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Author (up) Ahn, J.; Ahn, S.-E.; Yang, K.-S.; Kim, S.-W.; Oh, J. url  doi
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  Title Effects of a high level of illumination before sleep at night on chorioretinal thickness and ocular biometry Type Journal Article
  Year 2017 Publication Experimental eye Research Abbreviated Journal Exp Eye Res  
  Volume 164 Issue Pages 157-167  
  Keywords Vision  
  Abstract The choroid is affected by many factors. One of the factors, change in illumination has been suggested to influence choroidal thickness. However, the effects of bright light before sleep at night on the human eye are not well established. The purpose of this study was to investigate the effects of a high level of illumination in the evening on ocular measurements. Twenty-seven men with myopia spent seven consecutive nights in the sleep laboratory. During the first two nights, subjects were exposed to light at 150 lux between 20:00 and midnight. Then, for five consecutive nights, they were exposed to ambient light at 1000 lux between 20:00 and midnight. Ocular parameters and their diurnal variations were compared between the two periods and the effects of a high level of illumination were analyzed. After subjects were exposed to 1000 lux of illumination, axial length increased with borderline significance (p = 0.064). Macular volume and retinal thickness did not change. However, subfoveal choroidal thickness after exposure to 1000 lux of illumination (245.37 +/- 52.84 mum) was significantly lower than that after 150 lux of illumination (268.00 +/- 57.10 mum), (p < 0.001). Significant diurnal variations were found in mean keratometry (p = 0.039), intraocular pressure (IOP, p = 0.003), ocular perfusion pressure (OPP, p < 0.0001), macular volume (p = 0.019), and subfoveal choroidal thickness (p < 0.0001). A high level of illumination had significant effects on only IOP and OPP (p = 0.027 and 0.017, respectively). Bright light exposure before sleep at an intensity as high as 1000 lux reduced subfoveal choroidal thickness in healthy young men. In conclusion, diurnal variation in choroidal thickness can be affected by bright light exposure before sleep.  
  Address Department of Ophthalmology, Korea University College of Medicine, 73, Inchon-ro, Sungbuk-gu, Seoul 02841, South Korea. Electronic address: ojr4991@korea.ac.kr  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0014-4835 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:28887137 Approved no  
  Call Number LoNNe @ kyba @ Serial 1729  
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