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Author (up) Saini, C.; Hutton, P.; Gao, S.; Simpson, R.K.; Giraudeau, M.; Sepp, T.; Webb, E.; McGraw, K.J. url  doi
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  Title Exposure to artificial light at night increases innate immune activity during development in a precocial bird Type Journal Article
  Year 2019 Publication Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology Abbreviated Journal Comp Biochem Physiol A Mol Integr Physiol  
  Volume in press Issue Pages  
  Keywords Animals  
  Abstract Humans have greatly altered Earth's night-time photic environment via the production of artificial light at night (ALAN; e.g. street lights, car traffic, billboards, lit buildings). ALAN is a problem of growing importance because it may significantly disrupt the seasonal and daily physiological rhythms and behaviors of animals. There has been considerable interest in the impacts of ALAN on health of humans and other animals, but most of this work has centered on adults and we know comparatively little about effects on young animals. We exposed 3-week-old king quail (Excalfactoria chinensis) to a constant overnight blue-light regime for 6weeks and assessed weekly bactericidal activity of plasma against Escherichia coli – a commonly employed metric of innate immunity in animals. We found that chronic ALAN exposure significantly increased bactericidal activity and that this elevation in immune performance manifested at different developmental time points in males and females. Whether this short-term increase in immune activity can be extended to wild animals, and whether ALAN-mediated increases in immune activity have positive or negative fitness effects are unknown and will provide interesting avenues for future studies.  
  Address School of Life Sciences, Arizona State University, Tempe, AZ 85287, United States of America. Electronic address: Kevin.McGraw@asu.edu  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1095-6433 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:30974186 Approved no  
  Call Number GFZ @ kyba @ Serial 2291  
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