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Author (up) Berson, D.M.; Dunn, F.A.; Takao, M. url  doi
openurl 
  Title Phototransduction by retinal ganglion cells that set the circadian clock Type Journal Article
  Year 2002 Publication Science (New York, N.Y.) Abbreviated Journal Science  
  Volume 295 Issue 5557 Pages 1070-1073  
  Keywords Human Health; Animals; Axons/ultrastructure; *Biological Clocks; *Circadian Rhythm; Dendrites/ultrastructure; Isoquinolines; Kinetics; Light; *Light Signal Transduction; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells/chemistry/cytology/*physiology; Rod Opsins/analysis/physiology; Suprachiasmatic Nucleus/cytology/*physiology  
  Abstract Light synchronizes mammalian circadian rhythms with environmental time by modulating retinal input to the circadian pacemaker-the suprachiasmatic nucleus (SCN) of the hypothalamus. Such photic entrainment requires neither rods nor cones, the only known retinal photoreceptors. Here, we show that retinal ganglion cells innervating the SCN are intrinsically photosensitive. Unlike other ganglion cells, they depolarized in response to light even when all synaptic input from rods and cones was blocked. The sensitivity, spectral tuning, and slow kinetics of this light response matched those of the photic entrainment mechanism, suggesting that these ganglion cells may be the primary photoreceptors for this system.  
  Address Department of Neuroscience, Brown University, Providence, RI, 02912 USA. David_Berson@brown.edu  
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  Language English Summary Language Original Title  
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  Series Volume Series Issue Edition  
  ISSN 0036-8075 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:11834835 Approved no  
  Call Number LoNNe @ kagoburian @ Serial 720  
Permanent link to this record
 

 
Author (up) Buchar, J.; Thaler, K. openurl 
  Title Ãœber Pardosa atomaria (C .L. KOCH) und andere Pardosa-Arten an Geröllüfern in Süd- und Mitteleuropa. Type Journal Article
  Year 2002 Publication Linzer Biologischer Beitrag Abbreviated Journal  
  Volume Issue Pages 445–465  
  Keywords Plants  
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  Notes Approved no  
  Call Number LoNNe @ kagoburian @ Serial 659  
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Author (up) Cardiel, N.; Gorgas, J.; Gallego J.; Serrano, A.; Zamorano, J.; Garcia-Vargas, M.-L.; Gomez-Cambronero, P.; Filgueira, J.M. url  openurl
  Title Proper handling of random errors and distortions in astronomical data analysis. Type Report
  Year 2002 Publication Astronomical Telescopes and Instrumentation Abbreviated Journal  
  Volume Issue Pages 297–304  
  Keywords Remote Sensing  
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  Notes Approved no  
  Call Number LoNNe @ kagoburian @ Serial 911  
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Author (up) Cinzano, P. url  openurl
  Title Technical Measures for an effective limitation of the effects of light pollution. Type Journal Article
  Year 2002 Publication Abbreviated Journal  
  Volume Issue Pages  
  Keywords Lighting  
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  Notes Approved no  
  Call Number LoNNe @ schroer @ Serial 574  
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Author (up) Clark, B.A.J. url  openurl
  Title Outdoor Lighting and Crime, Part 1: Little or No Benefit. Type Journal Article
  Year 2002 Publication Abbreviated Journal  
  Volume Issue Pages  
  Keywords Society; Safety  
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  Notes Approved no  
  Call Number LoNNe @ kagoburian @ Serial 1016  
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