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Author Erren, T.C.; Morfeld, P.; Foster, R.G.; Reiter, R.J.; Gross, J.V.; Westermann, I.K.
Title Sleep and cancer: Synthesis of experimental data and meta-analyses of cancer incidence among some 1 500 000 study individuals in 13 countries Type Journal Article
Year 2016 Publication Chronobiology International Abbreviated Journal Chronobiol Int
Volume 33 Issue 4 Pages 325-350
Keywords Human Health; Cancer; chronodisruption; meta-analyses; napping; sleep and circadian rhythm disruption (SCRD); sleep duration; sleep quality; sleep timing; Circadian Rhythm; sleep; Oncogenesis
Abstract Sleep and its impact on physiology and pathophysiology are researched at an accelerating pace and from many different angles. Experiments provide evidence for chronobiologically plausible links between chronodisruption and sleep and circadian rhythm disruption (SCRD), on the one hand, and the development of cancer, on the other. Epidemiological evidence from cancer incidence among some 1 500 000 study individuals in 13 countries regarding associations with sleep duration, napping or “poor sleep” is variable and inconclusive. Combined adjusted relative risks (meta-RRs) for female breast cancer, based on heterogeneous data, were 1.01 (95% CI: 0.97-1.06). Meta-RRs for cancers of the colorectum and of the lung in women and men and for prostate cancer were 1.08 (95% CI: 1.03-1.13), 1.11 (95% CI: 1.00-1.22) and 1.05 (95% CI: 0.83-1.33), respectively. The significantly increased meta-RRs for colorectal cancer, based on homogeneous data, warrant targeted study. However, the paramount epidemiological problem inhibiting valid conclusions about the associations between sleep and cancer is the probable misclassification of the exposures to facets of sleep over time. Regarding the inevitable conclusion that more research is needed to answer How are sleep and cancer linked in humans? we offer eight sets of recommendations for future studies which must take note of the complexity of multidirectional relationships.
Address a Institute and Policlinic for Occupational Medicine, Environmental Medicine and Prevention Research , University of Cologne , Cologne , Germany
Corporate Author Thesis
Publisher Taylor & Francis Place of Publication Editor
Language English Summary Language English Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0742-0528 ISBN Medium
Area Expedition Conference
Notes PMID:27003385 Approved no
Call Number (up) IDA @ john @ Serial 1407
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Author van Schalkwyk, I.; Venkataraman, N.; Shankar, V.; Milton, J.; Bailey, T.; Calais, K.
Title Evaluation of the Safety Performance of Continuous Mainline Roadway Lighting on Freeway Segments in Washington State Type Report
Year 2016 Publication Abbreviated Journal
Volume Issue Pages
Keywords Public Safety; traffic; traffic safety; road safety; continuous roadway lighting; Washington; United States
Abstract Washington State Department of Transportation (WSDOT) evaluated continuous roadway lighting on mainline freeway segments in Washington State. An extensive literature review on the safety performance of roadway lighting was completed. As part of this research effort WSDOT developed multivariate random parameter (RP) models with specific lighting variables for continuous lighting on mainline freeway segments. Roadway lighting is often used as a countermeasure to address nighttime crashes and this research evaluates common assumption related to roadway lighting. The models developed for this research use crashes from the end of civil dusk twilight to the start of civil dawn twilight since lighting systems are of limited value outside these timeframes. Natural light conditions were estimated for crashes based on location and time of the crash event. Based on the RP results, the research team concludes that the contribution of continuous illumination to nighttime crash reduction is negligible. In addition to the findings on safety performance, a pilot LED project on US101 demonstrated that LED roadway lighting can significantly increase energy efficiency and environmental stewardship (e.g., reducing greenhouse gas emissions) while maintaining safety performance outcomes. The research team recommended modification to WSDOT design policy, including removal of the requirement of continuous mainline lighting and reduction of lighting where segment specific analysis indicates appropriate.
Address Washington State Department of Transportation 310 Maple Park Ave SE, Olympia, WA, USA
Corporate Author Thesis
Publisher Washington State Department of Transportation Place of Publication Editor
Language English Summary Language English Original Title
Series Editor Series Title WSDOT Research Report Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number (up) IDA @ john @ Serial 1427
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Author Vozzi, C.; Ramponi, R.
Title 2015 International Year of Light and beyond Type Magazine Article
Year 2016 Publication Journal of Optics Abbreviated Journal J. Opt.
Volume 18 Issue 1 Pages 010201
Keywords Commentary; International Year of Light; IYL; IYL2015; society
Abstract The 2015 International Year of Light and Light-based Technologies (IYL) is now approaching its end. It has been a year full of excitement worldwide, involving people of all ages in an incredible number of different activities
Address Institute for Photonics and Nanotechnologies (IFN-CNR) Piazza Leonardo da Vinci 32, I-20133 Milan, Italy
Corporate Author Thesis
Publisher IOP Place of Publication Editor
Language English Summary Language English Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 2040-8978 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number (up) IDA @ john @ Serial 1428
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Author Buijs, F.N.; Leon-Mercado, L.; Guzman-Ruiz, M.; Guerrero-Vargas, N.N.; Romo-Nava, F.; Buijs, R.M.
Title The Circadian System: A Regulatory Feedback Network of Periphery and Brain Type Journal Article
Year 2016 Publication Physiology (Bethesda, Md.) Abbreviated Journal Physiology (Bethesda)
Volume 31 Issue 3 Pages 170-181
Keywords Human health; circadian rhythm; suprachiasmatic nucleus; brain; clock genes; SCN; review; circadian desynchronization; shiftwork
Abstract Circadian rhythms are generated by the autonomous circadian clock, the suprachiasmatic nucleus (SCN), and clock genes that are present in all tissues. The SCN times these peripheral clocks, as well as behavioral and physiological processes. Recent studies show that frequent violations of conditions set by our biological clock, such as shift work, jet lag, sleep deprivation, or simply eating at the wrong time of the day, may have deleterious effects on health. This infringement, also known as circadian desynchronization, is associated with chronic diseases like diabetes, hypertension, cancer, and psychiatric disorders. In this review, we will evaluate evidence that these diseases stem from the need of the SCN for peripheral feedback to fine-tune its output and adjust physiological processes to the requirements of the moment. This feedback can vary from neuronal or hormonal signals from the liver to changes in blood pressure. Desynchronization renders the circadian network dysfunctional, resulting in a breakdown of many functions driven by the SCN, disrupting core clock rhythms in the periphery and disorganizing cellular processes that are normally driven by the synchrony between behavior and peripheral signals with neuronal and humoral output of the hypothalamus. Consequently, we propose that the loss of synchrony between the different elements of this circadian network as may occur during shiftwork and jet lag is the reason for the occurrence of health problems.
Address Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Ciudad Universitaria, Mexico; ruudbuijs(at)gmail.com
Corporate Author Thesis
Publisher American Physiological Society Place of Publication Editor
Language English Summary Language English Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1548-9221 ISBN Medium
Area Expedition Conference
Notes PMID:27053731 Approved no
Call Number (up) IDA @ john @ Serial 1429
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Author Lucas, M.A.; Chahl, J.S.
Title Challenges for biomimetic night time sky polarization navigation Type Conference Article
Year 2016 Publication Proceedings of the SPIE Abbreviated Journal Proc SPIE
Volume 9797 Issue Pages
Keywords Animals; detection of light; biology; polarization; navigation
Abstract Studies on some species of insects have shown them to use the polarization pattern cast by the moon in the night sky to control heading. Additional heading cues are of value to autonomous systems, since the earth’s magnetic field is not uniform, often not available and is substantially modified by local phenomena. In addition to the required low-light sensitivity of a night time polarization compass, additional complexities caused by the relative intensity of terrestrial sources must be overcome. We will show that the end result will tend to be a less reliable compass than the equivalent day time polarization device.
Address Univ. of South Australia, Australia
Corporate Author Thesis
Publisher SPIE Place of Publication Editor
Language English Summary Language English Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number (up) IDA @ john @ Serial 1430
Permanent link to this record