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Author Cho, C.-H.; Moon, J.-H.; Yoon, H.-K.; Kang, S.-G.; Geum, D.; Son, G.-H.; Lim, J.-M.; Kim, L.; Lee, E.-I.; Lee, H.-J. url  doi
openurl 
  Title Molecular circadian rhythm shift due to bright light exposure before bedtime is related to subthreshold bipolarity Type Journal Article
  Year 2016 Publication Scientific Reports Abbreviated Journal Sci Rep  
  Volume 6 Issue Pages 31846  
  Keywords Human Health  
  Abstract This study examined the link between circadian rhythm changes due to bright light exposure and subthreshold bipolarity. Molecular circadian rhythms, polysomnography, and actigraphy data were studied in 25 young, healthy male subjects, divided into high and low mood disorder questionnaire (MDQ) score groups. During the first 2 days of the study, the subjects were exposed to daily-living light (150 lux) for 4 hours before bedtime. Saliva and buccal cells were collected 5 times a day for 2 consecutive days. During the subsequent 5 days, the subjects were exposed to bright light (1,000 lux), and saliva and buccal cell samples were collected in the same way. Molecular circadian rhythms were analyzed using sine regression. Circadian rhythms of cortisol (F = 16.956, p < 0.001) and relative PER1/ARNTL gene expression (F = 122.1, p < 0.001) showed a delayed acrophase in both groups after bright light exposure. The high MDQ score group showed a significant delay in acrophase compared to the low MDQ score group only in salivary cortisol (F = 8.528, p = 0.008). The high MDQ score group showed hypersensitivity in cortisol rhythm shift after bright light exposure, suggesting characteristic molecular circadian rhythm changes in the high MDQ score group may be related to biological processes downstream from core circadian clock gene expression.  
  Address Department of Biomedical Science, Korea University College of Medicine, Seoul, South Korea  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2045-2322 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:27545669 Approved no  
  Call Number LoNNe @ kyba @ Serial (down) 1513  
Permanent link to this record
 

 
Author Quiles, C.L.; de Oliveira, M.A.B.; Tonon, A.C.; Hidalgo, M.P.L. url  doi
openurl 
  Title Biological adaptability under seasonal variation of light/dark cycles Type Journal Article
  Year 2016 Publication Chronobiology International Abbreviated Journal Chronobiol Int  
  Volume 33 Issue 8 Pages 964-971  
  Keywords Animals  
  Abstract 3A substantial amount of experimental models designed to understand rhythms entrainment and the effects of different regimens of light exposure on health have been proposed. However, many of them do not relate to what occurs in real life. Our objective was to evaluate the influence of “seasonal-like” variation in light/dark cycles on biological rhythms. Twenty adult male Wistar rats were assigned to three groups: control (CT), kept in 12:12 light/dark (LD) cycle; long photoperiod/short photoperiod (LP/SP), kept in 16.5:7.5 LD cycle for 18 days (phase A), then 17 days of gradual reductions in light time (phase B), then 18 days of shorter exposure (7.5:16.5 LD cycle, phase C); short photoperiod/long photoperiod (SP/LP) group, with same modifications as the LP/SP group, but in reverse order, starting phase A in 7.5:16.5 LD cycle. Activity and temperature were recorded constantly, and melatonin and cortisol concentrations were measured twice. Activity and temperature acrophases of all groups changed according to light. The correlation between activity and temperature was, overall, significantly lower for SP/LP group compared with LP/SP and CT groups. Regarding melatonin concentration, LP/SP group showed significant positive correlation between phase A and C (p = 0.018). Animals changed temperature and activity according to photoperiod and demonstrated better adaptability in transitioning from long to short photoperiod. Since this model imitates seasonal variation in light in a species that is largely used in behavioral experiments, it reveals promising methods to improve the reliability of experimental models and of further environmental health research.  
  Address b Pos-graduacao em Psiquiatria e Ciencias do Comportamento, Faculdade de Medicina (FAMED) , Universidade Federal do Rio Grande do Sul (UFRGS) , Porto Alegre , Brasil  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0742-0528 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:27222076 Approved no  
  Call Number LoNNe @ kyba @ Serial (down) 1512  
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Author Phelps, J. url  doi
openurl 
  Title A powerful non-pharmacologic treatment for mania – virtually Type Journal Article
  Year 2016 Publication Bipolar Disorders Abbreviated Journal Bipolar Disord  
  Volume 18 Issue 4 Pages 379-382  
  Keywords Commentary; Human Health  
  Abstract  
  Address Samaritan Mental Health, Corvallis, OR, USA  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1398-5647 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:27218661 Approved no  
  Call Number LoNNe @ kyba @ Serial (down) 1511  
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Author Voiculescu, S.E.; Duc, D.L.; Rosca, A.E.; Zeca, V.; Chitimus, D.M.; Arsene, A.L.; Dragoi, C.M.; Nicolae, A.C.; Zagrean, L.; Schöneberg, T.; Zagrean, A.-M. url  doi
openurl 
  Title Behavioral and molecular effects of prenatal continuous light exposure in the adult rat Type Journal Article
  Year 2016 Publication Brain Research Abbreviated Journal Brain Research  
  Volume 1650 Issue Pages 51–59  
  Keywords Animals  
  Abstract  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0006-8993 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number LoNNe @ kyba @ Serial (down) 1509  
Permanent link to this record
 

 
Author Lagiou, P. url  doi
openurl 
  Title Shedding light on the role of circadian disruption in breast cancer etiology Type Journal Article
  Year 2016 Publication European Journal of Epidemiology Abbreviated Journal Eur J Epidemiol  
  Volume 31 Issue 9 Pages 807-810  
  Keywords Commentary; Human Health  
  Abstract  
  Address Department of Epidemiology, Harvard T. H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA, 02115, USA. pdlagiou@med.uoa.gr  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0393-2990 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:27550370 Approved no  
  Call Number LoNNe @ kyba @ Serial (down) 1508  
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