|Home||<< 1 >>|
Rybnikova, N. A., Haim, A., & Portnova, B. A. (2016). Is Prostate Cancer Incidence Worldwide Linked to Artificial Light at Night Exposures? Earlier Findings' Revisit and Current Trends' Analysis. Arch Environ Occup Health, 72(2), 111–122.
Abstract: Widespread use of artificial light at night (ALAN) might contribute to the global burden of hormone-dependent cancers. However, previous attempts to verify this association in population-level studies have been sparse. Using the GLOBOCAN, US-DMSP and World Bank's 2010-2012 databases, we studied the association between ALAN and prostate cancer (PC) incidence in 180 countries worldwide, controlling for several country-level confounders. As our analysis indicates, the PC-ALAN association emerged marginally significant when year-2012 PC age-standardized rate data were compared with ALAN levels (t = 1.886, P<0.1); while this association emerged as more significant (t>2.7; P<0.01) when only 110 countries with well-maintained cancer registries were analyzed. Along with other variables, ALAN explains up to 79% of PC ASRs variability. PC-ALAN association appears to vary regionally, with the greatest deviations in Central Africa, Small Island Developing States, South East Asia and Gulf States.